Foundations

Steroid cream on the face: side effects, hidden steroids and how to stop safely

Dr Ong Jin Khang · MMC 45245 · LCP holder · The Retreat Clinic, Setia Alam

A steroid cream (a topical corticosteroid) calms inflammation, and on the face it is meant for short courses on a doctor's or pharmacist's advice. Used for weeks or months, it can thin the skin, show up blood vessels, cause acne-like spots and rosacea-like redness, and near the eyes it can raise eye pressure. Malaysia's drug regulator has also cancelled the notification of creams sold as cosmetics after finding a steroid in them. If you have been using such a cream, do not keep using one you cannot identify, and see a doctor for a plan to stop.

A generated image: a small open cream jar on warm paper beside a hand-drawn ink and watercolour cross-section of skin, with fine red blood vessels drawn beneath the surface. Not a photograph of a patient.

Know what is in the jar.

On this page
  1. What is a steroid cream, and why do doctors use it?
  2. How strong are steroid creams?
  3. Why is facial skin different?
  4. What happens if a steroid cream is used on the face for too long?
  5. What are the risks near the eyes?
  6. What is topical steroid withdrawal, and how sure are we about it?
  7. Can a whitening or miracle cream contain a steroid?
  8. I have been using a steroid cream on my face. What should I do?
  9. What does The Retreat Clinic offer here?

What is a steroid cream, and why do doctors use it?

A steroid cream is a topical corticosteroid, an anti-inflammatory medicine that goes on the skin. DermNet NZ, a dermatology reference, lists eczema and dermatitis as its main uses, and says it is usually applied once a day for 5 days to several weeks, then stopped or reduced.

Used that way, it works well. DermNet describes side effects as uncommon or rare when the cream is used appropriately under medical supervision. The trouble starts when a cream meant for a short course stays on the face for weeks or months, or when the person does not know it is a steroid at all.

How strong are steroid creams?

DermNet sorts them into four strength bands, and the band matters more than the brand. DermNet gives examples by generic name: mild (hydrocortisone), moderate (clobetasone butyrate, triamcinolone acetonide), potent (betamethasone valerate, mometasone furoate) and very potent (clobetasol propionate). Strength depends on the molecule, on the cream or ointment base, and on how thin the skin is. The same reference advises using the weakest steroid that does the job.

Which of these a pharmacist can hand over without a prescription in Malaysia depends on the product and its strength, so that is a question for a doctor or pharmacist. What the Ministry of Health's drug regulator, the National Pharmaceutical Regulatory Agency (NPRA), says in its public statements is that a cream containing betamethasone 17-valerate is a medicine that must be registered with the Drug Control Authority and used only on the advice of a health professional.

Why is facial skin different?

Facial skin is thin, and thin skin absorbs more medicine. DermNet notes that absorption is greatest through the skin of the eyelids, the genitals and skin creases, and is increased when the area is covered. The UK medicines regulator, the MHRA, asks doctors to tell patients how long to use a steroid cream, especially on sensitive areas such as the face.

New Zealand's medicines safety bulletin was firmer in 2005. It said steroid creams should not be used on the face except for brief periods, under two weeks, and then only for conditions that had not responded to other treatment. That bulletin is old, but DermNet's newer page on withdrawal still advises avoiding prolonged use of moderate to potent steroids on the face.

What happens if a steroid cream is used on the face for too long?

The skin thins, which is called atrophy. Small blood vessels become visible (telangiectasia) and the skin bruises easily. DermNet and the New Zealand bulletin both list these, and both say the risk is greater with the more potent steroids.

Rashes can follow. Perioral dermatitis is a rash of small red bumps around the mouth, nose and eyelids. Steroid rosacea is a rosacea-like redness of the middle of the face, with bumps, burning and visible vessels. DermNet says both can follow weeks to months of potent steroid use, and that steroid rosacea can become especially severe when the cream is stopped. A 2025 review in the Journal of Clinical and Aesthetic Dermatology lists perioral dermatitis, acne and flushing as effects on the face.

NPRA's own statements add acne-like spots and changes in skin colour. About betamethasone 17-valerate, NPRA says the skin of the face that the cream touches can become thin and easily irritated, break out in acne and change in pigment, and that the medicine can be absorbed into the bloodstream, where it can do harm. DermNet also lists extra hair growth in the treated patch, and says steroids can hide or worsen infections such as fungal infection of the skin and cold sores, so a rash that seems to improve under a steroid is not always settling. If acne-like spots are the main problem, the article on what a doctor checks first in adult acne sets out the usual causes.

What are the risks near the eyes?

The skin of the eyelids absorbs steroid readily. DermNet says excessive use over weeks to months might lead to glaucoma or cataracts. Glaucoma is damage to the eye's nerve, usually linked to raised pressure inside the eye, and it can lead to loss of vision.

A 2019 report in the Medical Journal of Australia gives a concrete case. A woman who had used hydrocortisone 1 per cent cream daily on her eyelids for 3 to 4 months was found to have eye pressure of about 42 and 40 (in mmHg, the unit eye doctors use). Two weeks after she stopped the cream, it was 15 and 18, on a single glaucoma eye drop. She had been diagnosed with glaucoma in one eye many years earlier, and the authors list myopia (short-sightedness), connective tissue disease and a personal or family history of glaucoma as risk factors. They advise eye pressure and optic nerve checks for anyone on these treatments. A 2025 review also cites a UK study in which the risk of cataract was higher with steroid creams used elsewhere on the body, though lower than with steroid tablets, eye drops or inhalers.

Anyone who has used a steroid cream on or near the eyelids for more than a few weeks should have their eyes checked, and the same goes for long-standing redness around the eyes, which is covered in the article on rosacea and the eye.

What is topical steroid withdrawal, and how sure are we about it?

The MHRA reviewed it in 2021. It said severe reactions can rarely follow stopping a steroid cream, usually after long or inappropriate use of a moderate or high-potency product, and that it could not estimate how often this happens. The signs it asked doctors to look for are burning rather than itch as the main symptom, redness that spreads beyond the area treated, and a rash in unusual places. It said reactions can develop after daily use for longer than a year, and in children after as little as two months of daily use, and that the face and genitals are most often affected. Symptoms usually start within days to weeks of stopping.

DermNet calls it a rare rebound reaction and says its frequency is unknown. It says doctors have no agreed diagnostic criteria, that a withdrawal reaction is hard to tell from a flare of the original condition, and that no treatment has been shown to shorten recovery. It describes a papulopustular form, with bumps and pustules, that often follows use for pigmentation or cosmetic reasons. Most people recover within about three months, and a small minority take up to five years. The US National Eczema Association says withdrawal has been reported mostly by patients and is under-researched, and that it can be mistaken for the eczema itself.

So the fair summary is that it is recognised by the UK regulator, rare on its account and still poorly measured. DermNet is explicit that this should not stop anyone from having a steroid cream they genuinely need. It is a reason to ask a doctor for a plan. A short, supervised course remains the right tool for many skin conditions.

Can a whitening or miracle cream contain a steroid?

Yes, and NPRA has said so in public. Cosmetics sold in Malaysia are notified to NPRA, and they are not allowed to contain scheduled poisons. NPRA's page of cancelled cosmetic notifications lists products withdrawn after it found prohibited substances, including scheduled poisons, in them. Many entries name betamethasone 17-valerate, sometimes with mercury and sometimes with hydroquinone and tretinoin. When this article was written, the most recent entry naming it was dated 2 April 2026. In each statement NPRA says the notification was cancelled and the product may no longer be sold in Malaysia.

Two things follow. A label, a shop or a well-known seller cannot tell you what is in the jar, which is why NPRA's statements tell the public to check a cosmetic's notification status on its website. And a notification that exists today can be cancelled later, so check when you buy and again if a product appears in the news. The steps are in the KKM check for creams, injections and slimming pens, and the mercury side is in the article on whitening creams and mercury. If the reason for the cream is dark patches, melasma creams in Malaysia sets out which medicines are legal and how they are meant to be used.

I have been using a steroid cream on my face. What should I do?

Do not keep using a cream if you do not know what is in it, and do not guess your own way out either. See a doctor and bring the jar and its box. NPRA tells people who have been using the creams it cancelled to stop using them and to see a health professional if they have any discomfort or reaction.

The plan matters because the way out depends on how long and how strong. DermNet says whether to stop at once or step down gradually is debated, and for steroid rosacea it describes applying less often and moving to a weaker steroid to limit rebound flares. The MHRA says that if skin gets worse within two weeks of stopping, you should not start the cream again without talking to your doctor. A doctor can also tell a flare of the original condition from withdrawal, and can arrange an eye check if the cream was used near the eyes.

If you think a medicine has caused a side effect, you can report it yourself to NPRA through its online ConSERF form; for a cosmetic, NPRA takes complaints through its page on notified cosmetic products. Each route, and what to keep, is set out in how to report a side effect in Malaysia.

What does The Retreat Clinic offer here?

The Retreat Clinic is an aesthetic clinic, not an eczema or dermatology service. Dr Ong can examine the skin, say what it looks like (thinning, visible vessels, leftover marks) and tell you whether it is a matter for him or for someone else. A dermatologist is the right doctor for eczema and for a severe withdrawal reaction, and an eye doctor is the right one for eye pressure. The clinic does not run a programme for steroid withdrawal, and it does not offer vascular lasers, which is explained in why we do not offer IPL or a vascular laser.

Knowing what is in the jar is the first step. The second is having someone who can examine the skin tell you what it has been doing.

Common questions

Is it safe to use steroid cream on the face?

Only for a short course on the advice of a doctor or pharmacist. Facial skin is thin and absorbs more medicine, and a 2005 New Zealand safety bulletin advised against facial use beyond brief periods, under two weeks. Long use can thin the skin, show blood vessels and cause rashes such as perioral dermatitis and steroid rosacea.

How do I know if my whitening cream has a steroid in it?

You cannot tell by looking at the jar. NPRA has cancelled the notification of creams sold as cosmetics after finding betamethasone 17-valerate, sometimes with mercury, hydroquinone or tretinoin. Check the product's notification status on the NPRA website, and see a doctor if the skin has thinned, reddened or broken out.

What is topical steroid withdrawal?

A reaction that can follow stopping a steroid cream after long use, with burning, redness and peeling. The UK MHRA calls severe cases rare and could not estimate how often they occur, and DermNet says there are no agreed diagnostic criteria and no treatment proven to shorten recovery. A doctor can tell it from a flare of the original condition.

How do I stop a steroid cream safely?

See a doctor first rather than stopping or tapering by guesswork. DermNet says stopping at once or stepping down is debated, and the MHRA advises not restarting the cream without a doctor's advice if the skin worsens within two weeks of stopping. If the cream was used near the eyes, ask for an eye pressure check.

Sources

  1. MHRA. Topical corticosteroids: information on the risk of topical steroid withdrawal reactions. Drug Safety Update, volume 15, issue 2, 15 September 2021 The UK regulator's review. Severe reactions after stopping are rare and usually follow long or inappropriate use of moderate or high-potency products; 55 Yellow Card reports were found, frequency cannot be estimated, the face and genitals are most often affected, and patients whose skin worsens within two weeks of stopping should not restart without medical advice.
  2. DermNet NZ. Topical corticosteroid withdrawal. Reviewed July 2023, minor update January 2025 A dermatology reference. A rare rebound reaction of unknown frequency, with no agreed diagnostic criteria, no treatment proven to shorten recovery, and a papulopustular form that often follows use for pigmentation or cosmetic reasons. It states that concern about withdrawal should not prevent adequate treatment.
  3. National Eczema Association (US). Topical steroid withdrawal. Read 2 November 2026 States that withdrawal has been reported anecdotally by patients, is recognised by some clinicians and remains under-researched, and is often mistaken for atopic dermatitis; advises seeing a clinician to rule out an eczema flare.
  4. DermNet NZ. Topical steroids (corticosteroid creams). Author A Oakley, last updated 4 January 2016 Uses (eczema and dermatitis), the four potency bands with generic examples, typical once-daily use for 5 days to several weeks, and the local side effects: thinning, bruising, visible vessels, extra hair, perioral dermatitis and steroid rosacea. Eyelid skin absorbs most, and excessive use over weeks to months might lead to glaucoma or cataracts. An older page; not re-dated by the publisher.
  5. DermNet NZ. Steroid rosacea. Reviewed June 2014 A rosacea-like rash of the middle of the face caused by potent topical steroids or their withdrawal, a variant of perioral dermatitis; severe when the steroid is stopped, with slow withdrawal advised.
  6. Medsafe (New Zealand). Topical corticosteroids on the face. Prescriber Update 26(2), December 2005 Facial use can cause atrophy, visible vessels, bruising, rash around the mouth and eyes and worsening rosacea, with 14 New Zealand reports of pigment change, stretch marks and thinning; use on the face only for short periods, under two weeks. The publisher notes the article is more than five years old.
  7. DiRuggiero D, DiRuggiero M. Beyond skin deep: the systemic impact of topical corticosteroids in dermatology. Journal of Clinical and Aesthetic Dermatology, 2025;18(1-2 Suppl 1):S16-S20 A review. Facial use carries higher risk; perioral dermatitis, acne and flushing are listed as effects, ocular hypertension, glaucoma and loss of vision as eye effects, and a UK case-control study found cataract risk raised (odds ratio 1.43) with topical steroids used away from the eye.
  8. Chan HHL, Salmon JF. Glaucoma caused by topical corticosteroid application to the eyelids. Medical Journal of Australia, 2019;210(4) A case in which 3 to 4 months of daily hydrocortisone 1 per cent cream on the eyelids was followed by eye pressure of 42 and 40 mmHg, falling to 15 and 18 within two weeks of stopping. Lists myopia, connective tissue disease and a personal or family history of glaucoma as risk factors and advises pressure and optic nerve checks.
  9. NPRA, Ministry of Health Malaysia. Media statement on cosmetic products found to contain scheduled poisons (file dated February 2025) In Malay. Lists creams found to contain mercury, hydroquinone, tretinoin and betamethasone 17-valerate, with their notifications cancelled by the Director of Pharmaceutical Services. Says these are medicines that must be registered with the Drug Control Authority and used only on a health professional's advice, and describes the effects of betamethasone 17-valerate on facial skin (thinning, irritation, acne, pigment change, absorption into the bloodstream).
  10. NPRA, Ministry of Health Malaysia. Media statement on cosmetics found to contain scheduled poisons, 8 November 2025 In Malay. A cream found to contain mercury and betamethasone 17-valerate, notification cancelled and sale no longer allowed; the same description of effects; advises people using such cosmetics to stop and see a health professional if they have discomfort, and to check notification status on the NPRA website.
  11. NPRA, Ministry of Health Malaysia. Cancellation of notified cosmetic products. Read 2 November 2026 The running list of cosmetics whose notification was cancelled for adulteration, with entries by year naming betamethasone 17-valerate, mercury, hydroquinone and tretinoin; on 2 November 2026 the latest entry naming betamethasone 17-valerate is dated 2 April 2026.
  12. NPRA, Ministry of Health Malaysia. Reporting side effects to medicines (ConSERF). Read 2 November 2026 Consumers can report suspected side effects of medicines through the online ConSERF form, even when unsure the medicine caused them; notified cosmetics and quality reports go through NPRA's public enquiry page.

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