Foundations

How long does XERF last, and when should it be repeated?

Dr Ong Jin Khang · MMC 45245 · LCP holder · The Retreat Clinic, Setia Alam

Nobody yet knows exactly: the published XERF studies followed people for only 90 days, so no figure exists for how long a result lasts, and any number you are given is a plan, not a measurement. The clinic's page says maintenance is typically advised every six to twelve months, as a protocol and not a promise, and a repeat is decided at a review, not by a calendar.

Watercolour plate of a skin cross-section framed by leaves, lying on a wooden table by a window beside a cup of tea

A repeat is a review decision, not a date.

How long does XERF last?

No one knows exactly, because it has not been measured. The two published XERF studies followed people for three months at most, and neither tried to find out when the effect fades. The clinic's page describes the collagen change as building over months, says maintenance is typically advised every six to twelve months, and that there is no proven long-term durability figure for this device yet, so it frames the interval as a protocol, not a promise. It is not a measured lifespan.

So a promise of "lasts one year" or "lasts two years" from any source goes beyond the evidence. The honest answer is a range of review points and a method for choosing among them, and the rest of this page sets out both.

What do the XERF studies show about timing?

The larger one, by Weiss and colleagues, treated 39 people at four United States sites. The protocol allowed up to three sessions four weeks apart, and all 39 finished after two. Clinicians rated improvement in 84.6% of people at 30 days and in 92.3% at 90 days, and patient satisfaction was scored at four or above out of six by 79.5% at 30 days and 84.6% at 90 days. No lasting adverse events were reported. The study called itself short-term, had no control group, relied on the investigators for the ratings, and was supported by the maker with the device, consumables and a modest research grant.

The smaller one, by Erlich and colleagues, reviewed 16 women who had a single session. Their measurements at immediate, one-month and three-month visits showed the eyebrows and upper eyelids rising progressively, with wrinkle severity, evenness and pore size improving. The authors describe the findings as preliminary and ask for larger controlled studies. Together, these say how a result forms over three months. They do not say what happens at six, twelve or twenty-four. For how the studies fit with the rest of the evidence see a doctor's evidence review of XERF.

What does the wider radiofrequency evidence say about durability?

It can be used as context but not as a substitute. XERF is a monopolar radiofrequency device, and older devices of the same class have longer follow-up. These are other machines, so their numbers cannot be transferred to XERF.

In a 2007 study of 66 people with moderate laxity, a multiple-pass technique with an earlier device was followed to six months: 92% had a measurable improvement in overall appearance and independent photographic review showed improvement in 84%. The same paper reports that objective measurements made with a skin-stiffness device showed improvement that diminished with time. A 2021 trial of a later device followed 40 people aged 30 to 60 with mild to moderate laxity for 180 days, and 73% were rated improved at six months. The lesson is modest: in this class, appearance scores held at six months in most people, instrument measures tended to drift, and follow-up in the published literature tends to stop at about six months. The article on Thermage, XERF and monopolar radiofrequency compares the devices.

What does ageing do after XERF?

It carries on. The Erlich paper begins from the point that the vertical anchoring system of the face, the collagen-rich network that supports it, progressively deteriorates with age. A treatment can improve how that network behaves for a time. It does not stop the process, so the face at two years differs from the face at six months partly because of the treatment and partly because of two more years.

That is one reason a fixed expiry date is hard to give. A result is a comparison with where you started, and you keep moving. Sun exposure, weight change and the skin you began with also vary between people, and the studies were not built to separate those from the treatment effect.

When should XERF be repeated?

When the doctor, looking at your skin, thinks another session would help. The clinic's course is two sessions four to six weeks apart, and maintenance, when it is wanted, is typically advised every six to twelve months, at a review where the doctor compares how the skin looks now with how it looked before. If the change is still present, waiting may be the right answer. If laxity has crept back and the skin is still suitable, another session may be offered. The page on who XERF is for and who it isn't explains how suitability is judged, and the same judgement applies at a repeat.

This is a decision, not a schedule. A calendar date has the problem that it treats everyone as the same, and it can lead to treatment that adds little. The cost article, what the XERF fee is made of, looks at how a maintenance session is quoted, without giving a price.

Is it safe to repeat XERF sooner or more often?

Nobody has tested it. The 39-person study allowed up to three sessions four weeks apart and found no lasting adverse events, but all of those people stopped at two, and no published XERF study repeated treatment months later. A repeat sooner than the doctor advises therefore has no evidence behind it, and more energy is not the same as more benefit. What can be said is that normal after-treatment redness and mild swelling are described in the aftercare article, and that a blister, burn or lasting change in colour or sensation should be reported to the clinic.

How does the doctor judge whether a repeat is needed?

By comparison with a record made at the start. In the 39-person study, standardised clinical photographs were taken at baseline, 30 days and 90 days and rated on a five-point global improvement scale, a score of three meaning improved. A clinic can use the same principle: photographs under the same light and angle at assessment, then at review, together with what you notice and what the doctor feels and sees in the skin. Photographs here are a measuring tool for the review, and they prove nothing to anyone else.

A review that rests on memory ("I think it looked tighter last year") is weaker than one that rests on a baseline. It is reasonable to ask whether the clinic takes one.

What should I ask a clinic that quotes a duration?

Ask what the number is based on. A figure from a study of this device, with its follow-up length, is one thing. A figure borrowed from another machine, or from the clinic's own habit, is another. For XERF the published follow-up is 90 days, so any longer figure is the clinic's protocol or an estimate, and it should be described as that. Ask also what happens if the review finds the result has held, and whether you are expected to book the next session at the time you pay for the first.

What if I do not see a change?

Check the timing first. The studies rated change at 30 and 90 days, and the brow measured by Erlich and colleagues kept rising over three months. A judgement at two weeks is too early. If at 90 days the change is small, that is a question for a review, not a reason to book another session automatically. The doctor may find that the concern is volume, movement or excess skin, which radiofrequency does not address. The first article on this device, does XERF actually work, and the page on XERF skin tightening cover what to expect, and the comparison XERF vs Ultherapy vs HIFU vs microneedle RF sets out the other tools.

The honest complication

Everything on this page about XERF comes from 55 people followed for up to three months, in two small studies without control groups, one with the device and a research grant supplied by the maker. Everything about duration beyond that comes from other machines. A result that holds at six months in other studies does not prove XERF holds, and the opposite is also unproven. The only reliable method is the one the clinic describes: measure at the start, review, and decide from what you see.

Common questions

How long does XERF last?

No study has measured it. The published XERF studies followed people for 90 days, so there is no proven duration. The clinic's page says maintenance is typically advised every six to twelve months, as a protocol and not a promise of how long a result will last.

How often can you repeat XERF?

There is no published study of repeating XERF at a set interval. The clinic's course is two sessions four to six weeks apart, and later sessions are chosen at a review, from how the skin looks compared with before. The doctor decides whether another session is useful, and sometimes the answer is to wait.

When will I see XERF results?

Gradually. In the larger study, clinicians rated 84.6% of 39 people improved at 30 days and 92.3% at 90 days, and a smaller study measured the brow rising over three months. Change builds over months as collagen remodels, so a result at two weeks is not the final picture.

How many XERF sessions do I need?

The clinic's course is two sessions four to six weeks apart, then a review. The larger study treated 39 people twice, four weeks apart, though its protocol allowed up to three, and everyone finished after two. The plan is set at the assessment for your skin.

Does XERF last longer than Ultherapy?

No study has compared them for duration, so nobody can say. They are different technologies, radiofrequency and focused ultrasound, with different evidence. The article that compares them sets out what each reaches and what is known.

If you need more information, you can always contact us.